Primary Identifier | MGI:3577073 | Allele Type | QTL |
Gene | Scc13 | Inheritance Mode | Not Specified |
Strain of Origin | BALB/cHeA | Is Recombinase | false |
Is Wild Type | false |
description | Animals heterozygous at Scc13 and homozygous for STS/A-derived alleles at Scc14 exhibit the greatest susceptibility to AOM-induced colon tumors. Scc13 also shows suggestive interaction with Ptprj on mouse Chromosome 2, and Scc14 shows suggestive interaction with Scc4 on mouse Chromosome 17. |
molecularNote | Heterozygosity for this allele in conjunction with Scc14 confers colon tumor susceptibility. |