| Primary Identifier | MGI:3577076 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Safb |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 7-13 were repd with a IRES-LacZ-neo cassette. These exons encoded the ERalpha interaction domain and RD. RT-PCR analysis demonstrated absence of the C-terminal transcript in mutant brain and testis. Immunoblot confirms the absence of full-length protein, as well as a smaller truncated protein, in mutant brain and embryo samples. |
