Primary Identifier | MGI:3577079 | Allele Type | QTL |
Gene | Scc14 | Inheritance Mode | Not Specified |
Strain of Origin | STS/A | Is Recombinase | false |
Is Wild Type | false |
description | Animals heterozygous at Scc13 and homozygous for STS/A-derived alleles at Scc14 exhibit the greatest susceptibility to AOM-induced colon tumors. Scc13 also shows suggestive interaction with Ptprj on mouse Chromosome 2, and Scc14 shows suggestive interaction with Scc4 on mouse Chromosome 17. |
molecularNote | This allele in conjunction with Scc13 confers colon tumor susceptibility compared to BALB/cHeA. |