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Allele : Tcra-J<tm2.1Krg> T cell receptor alpha, joining region; targeted mutation 2.1, Michael S Krangel
Primary Identifier  MGI:3577333 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Tcra-J
Transmission  Germline Strain of Origin  129S/SvEv x C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The Trja49 promoter (Rr319) and gene segment were replaced with a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent cre-mediated recombination. No gross deficiency was found in alphabeta TCR expression or alphabeta T cell development in mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • Tcra<tm2Krg>,
  • DeltaJ49,
  • Tcra<tm2Krg>,
  • DeltaJ49
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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