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Allele : Gsk3a<tm1Dral> glycogen synthase kinase 3 alpha; targeted mutation 1, Dario R Alessi

Primary Identifier  MGI:3578225 Allele Type  Targeted
Attribute String  Not Specified Gene  Gsk3a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace serine 21, located on exon 1, with alanine (S21A). A floxed neomycin resistance cassette was inserted at the 3' end of exon 1. The neomycin cassette was subsequently excised from properly targeted ES cells by transient transfection with a cre expressing plasmid.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • GSK3alpha<21A>,
  • GSK3alpha<21A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

46 Publication categories

Trail: Allele