| Primary Identifier | MGI:3578661 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Zfp36l2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector containing a PGK-neo was inserted into exon 1, 30 bp downstream from the ATG. Northern and Western blot analyses confirmed disruption of transcript and protein, respectively, from exon 1. A transcript was found that appeared to result from the fusion of exon 2 to 403 bp from the 3' end of the intron instead of to the neo transcript. A truncated protein was also found at significantly reduced levels than wild-type. |
