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Allele : Cbfb<tm1Lhc> core binding factor beta; targeted mutation 1, Lucio H Castilla

Primary Identifier  MGI:3579250 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Cbfb
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  ES cells containing Cbfbtm1Ppl were targeted a second time to insert a floxed cassette encompassing exons 5 and 6, as well as the bovine growth hormone polyA signal and a PGK-hygro cassette into the Msc1 site in intron 4. This design allows the wild-type Cbfb transcript to be expressed. Cre expression would remove the cassette and restore expression of the knockin allele.
  • mutations:
  • Insertion
  • synonyms:
  • Cbfb<56M>,
  • Cbfb<56M>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

21 Publication categories