First Author | Vassileva G | Year | 1997 |
Journal | Brain Res Mol Brain Res | Volume | 46 |
Issue | 1-2 | Pages | 333-7 |
PubMed ID | 9191112 | Mgi Jnum | J:40442 |
Mgi Id | MGI:87786 | Doi | 10.1016/s0169-328x(97)00081-8 |
Citation | Vassileva G, et al. (1997) Absence of neuroanatomical and behavioral deficits in L7/pcp-2-null mice. Brain Res Mol Brain Res 46(1-2):333-7 |
abstractText | L7/pcp-2 is expressed exclusively in cerebellar Purkinje and retinal bipolar neurons. While the function of L7/pcp-2 is unknown, its mRNA is trafficked into dendrites, suggesting a role in dendritic physiology. To elucidate its function, L7/pcp-2-null mice were generated. These mice are neurologically normal with no signs of cerebellar or retinal dysfunction. The mice are indistinguishable from wild-type littermates with regards to gross neuroanatomy and fine structure of Purkinje cell dendrites. |