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Allele : Kras<tm1(Hras)Rdl> Kirsten rat sarcoma viral oncogene homolog; targeted mutation 1, Roberto Di Lauro

Primary Identifier  MGI:3581451 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Kras
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing Hras1 cDNA and a neo was fused in-frame with exon 2 such that synthesis of any Kras product would be abolished. Kras protein was undetectable in mutants. Hras1 protein was demonstrated to be present in brain, heart, liver, lung and spinal cord of mutants.
  • mutations:
  • Insertion
  • synonyms:
  • HrasKI,
  • Kras<(Hras)>,
  • HrasKI,
  • Kras<(Hras)>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele