| Primary Identifier | MGI:3581661 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Igh-J |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting construct was designed to insert a rearranged H chain of a physiologically selected ssDNA-binding antibody into the locus. The DQ52 and JH elements were deleted upon recombination. Flow cytometry demonstrated that 67% of heterozygous mice expressed only the mutant allele, and up to 31% expressed the endogenous allele exclusively. |
