Primary Identifier | MGI:3580157 | Allele Type | Transgenic |
Attribute String | Transactivator | Gene | Tg(Pcp2-tTA)3Horr |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
description | Transgene mRNA levels in cerebella of mice of nine independent transgenic lines were assayed by Northern blot analysis of cerebellar extracts. The highest-expressing line was selected to cross with mice bearing a TetO-driven transgene. |
molecularNote | This transgene expresses the tetracycline transactivator (tTA) under control of the 5' sequences, including the first exon, the first intron and part of the second exon, of the Purkinje-cell specific mouse Purkinje cell protein 2 gene. |