Primary Identifier | MGI:3580645 | Allele Type | Spontaneous |
Gene | Hr | Inheritance Mode | Recessive |
Strain of Origin | Mixed stock | Is Recombinase | false |
Is Wild Type | false |
description | Direct Submssion mutation arose on a (JH x Sb)F1 where JH is a (C3H/Rl x 101)F1 and Sb is a (SEC/El x C57BL/RlEl)F1 and then maintained on a C3H/Rl x C57BL/10Rl background. (J:156918) |
molecularNote | A single nucleotide change (from C to T) was identified at coding nucleotide 2440. This change in exon 12 causes a premature stop codon at arginine 814 (p.R814*). |