| First Author | Angel JM | Year | 1989 |
| Journal | J Natl Cancer Inst | Volume | 81 |
| Issue | 21 | Pages | 1652-5 |
| PubMed ID | 2552132 | Mgi Jnum | J:10061 |
| Mgi Id | MGI:58518 | Doi | 10.1093/jnci/81.21.1652 |
| Citation | Angel JM, et al. (1989) Genetics of N-methyl-N-nitrosourea induction of thymic lymphomas in AKR/J mice: assignment of a susceptibility gene to mouse chromosome 7. J Natl Cancer Inst 81(21):1652-5 |
| abstractText | Treatment of young AKR/J mice with N-methyl-N-nitrosourea (MNU) results in the induction of a high incidence of thymic lymphomas occurring between 4 and 6 months of age. The tumor incidence is higher and the latency period is shorter than that observed in other MNU-treated mouse strains. Analysis of tumor incidence in crosses of AKR/J with C57L/J mice indicates that several genes influence the incidence and latency of MNU-induced thymic lymphomas. One of these genes appears to be tightly linked to the albino locus of chromosome 7. |
