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Allele : Abcc3<tm1Bor> ATP-binding cassette, sub-family C member 3; targeted mutation 1, Piet Borst

Primary Identifier  MGI:3582301 Allele Type  Targeted
Attribute String  Null/knockout Gene  Abcc3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  4.9 kb of sequence containing exons 2-8, encoding amino acids 16-331, was replaced with a hygromycin resistance gene driven by Pgk1, and resulted in a frame shift that led to an early stop codon immediately after exon 1. Immunoblotting of various tissues in mutants demonstrated the absence of protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mrp3<->,
  • Mrp3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele