Primary Identifier | MGI:3582550 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tnfrsf14 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2, 3, and the 5' region of exon 4 were replaced by an intron gene trap cassette encompassing an engrailed-2 splice acceptor sequence, a beta-gal cassette, and a neomycin gene resistance cassette. Northern blot analysis of RNA from splenic tissues confirmed the null mutation. |