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Publication : pain1: a neuropathic pain QTL on mouse chromosome 15 in a C3HxC58 backcross.

First Author  Devor M Year  2005
Journal  Pain Volume  116
Issue  3 Pages  289-93
PubMed ID  15979798 Mgi Jnum  J:99476
Mgi Id  MGI:3582605 Doi  10.1016/j.pain.2005.04.023
Citation  Devor M, et al. (2005) pain1: A neuropathic pain QTL on mouse chromosome 15 in a C3HxC58 backcross. Pain 116(3):289-93
abstractText  We have produced a backcross (BC) population of 267 mice from the parental strains C3H/HeN and C58/J. The mice were phenotyped for neuropathic pain using the neuroma model. Subsequently all BC mice were genotyped in a region of chromosome 15 that has been previously suggested to contain a quantitative trait locus (QTL) for this trait. We have confirmed the linkage of the QTL, named pain1, to the central region of chromosome 15. Our finding provides the necessary robustness to justify efforts towards identification of the underlying gene.
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