| First Author | Yamada S | Year | 2004 |
| Journal | Biochem Biophys Res Commun | Volume | 316 |
| Issue | 2 | Pages | 580-7 |
| PubMed ID | 15020257 | Mgi Jnum | J:88845 |
| Mgi Id | MGI:3037341 | Doi | 10.1016/j.bbrc.2004.02.089 |
| Citation | Yamada S, et al. (2004) Novel testis- and embryo-specific isoforms of the phosphofructokinase-1 muscle type gene. Biochem Biophys Res Commun 316(2):580-7 |
| abstractText | We have identified novel transcriptional isoforms of the human and mouse genes encoding muscle type phosphofructokinase-1 (PFK-M). These isoforms are expressed specifically in the testis and in the mid-gestation embryo, and have been termed TE-PFK-M (testis- and embryo-specific PFK-M). The 5'UTR of TE-PFK-M is composed of three newly identified exons that lie much farther upstream of the PFK-M coding region than the previously characterized 5'UTR. In addition, this upstream region encodes a series of small polyadenylated transcripts, some of which share the same exons found in the 5'UTR of TE-PFK-M, and which may play some role in regulating TE-PFK-M expression. These findings indicate an even more complex level of control of PFK-M expression than previously thought. |
