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Allele : Arhgef1<tm1Kdf> Rho guanine nucleotide exchange factor 1; targeted mutation 1, Klaus-Dieter Fischer

Primary Identifier  MGI:3582489 Allele Type  Targeted
Attribute String  Null/knockout Gene  Arhgef1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin cassette replaced bp 1513-1651 including exon sequences of the DH domain encoding for amino acid residues 476-521. Immunoblot analysis of total spleen cell lysates revealed that homozygous mutants do not express protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Lsc<->,
  • Lsc<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories