|  Help  |  About  |  Contact Us

Allele : Bdnf<tm1Krj> brain derived neurotrophic factor; targeted mutation 1, Kevin R Jones

Primary Identifier  MGI:3582638 Allele Type  Targeted
Attribute String  Conditional ready, No functional change, Reporter Gene  Bdnf
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to flank the pro encoding region and mature hormone-encoding region of exon V with loxP sites, with a trimerized polyadenylation signal upstream of the 3' loxP sequence and a lacZ gene and FRT-flanked neomycin resistance cassette downstream of the 3' loxP sequence. Cre mediated excision would enable transcription and translation of lacZ in place of Bdnf.
  • mutations:
  • Insertion
  • synonyms:
  • BDNF-loxp,
  • BDNF<lox>,
  • Bdnf<klox>,
  • Bdnf<klox>,
  • BDNF-LSL-LacZ,
  • BDNF-loxp,
  • BDNF<lox>,
  • BDNF-LSL-LacZ
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

33 Publication categories