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Allele : Gsdme<tm1Ant> gasdermin E; targeted mutation 1, University of Antwerp

Primary Identifier  MGI:3583715 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gsdme
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A hygromycin resistance cassette flanked by loxP sites replaced exon 8 via homologous recombination. An additional loxP site was inserted between exons 6 and 7. Without cre recombinase exposure this allele was found by RT-PCR to produce appropriately aberrant transcript and western blot analysis failed to detect the protein in homozygotes.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories