| Primary Identifier | MGI:3582830 | Allele Type | Targeted |
| Gene | Kras | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | In one homologous recombination event an IRES Beta-geo cassette was inserted into the 3' untranslated region and in a second homologous recombination event a mutation changing glycine codon 12 in exon 1 into a valine (p.G12V) was inserted along with a loxP site flanked transcriptional stop and hygromycin resistance gene cassette. This resulted in bicistronic Cre recombination-dependent expression of the oncogenic Kras allele and Beta-geo. |
