Primary Identifier | MGI:3583807 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ptk2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was deleted via cre-mediated excision, resulting in a frame-shift mutation and the direct splicing of exon 2 to exon 4, and the production of a truncated protein of approximately 70 amino acids. Western blot of E8.5 lysates confirmed absence of protein in embryos. |