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Allele : Hipk1<tm1Mak> homeodomain interacting protein kinase 1; targeted mutation 1, Tak Wah Mak

Primary Identifier	MGI:3584135	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Hipk1
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting vector was designed to replace 2.7 kb of genomic DNA containing exon 1, encoding the putative kinase domain, with a neomycin resistance gene. Northern blot of mutant MEFs confirmed successful targeting.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
HIPK1<->,
HIPK1<->

earliestPublication:
Kondo S, et al. (2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proc Natl Acad Sci U S A 100(9):5431-6

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

6 Publication categories

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