| Primary Identifier | MGI:3584444 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Polg |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Mice carrying the floxed allele Polgtm1Lrsn were crossed with mice expressing cre ubiquitously, causing the removal of exon 3. Deletion of exon 3 results in a frameshift mutation leading to a stop codon early in exon 4 and the loss of nearly all active domains of the locus. |
