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Allele : Dnmt1<MommeD2> DNA methyltransferase 1; modifiers of murine metastable epiallele D2

Primary Identifier	MGI:3586549	Allele Type	Chemically induced (ENU)
Gene	Dnmt1	Inheritance Mode	Semidominant
Strain of Origin	FVB/N	Is Recombinase	false
Is Wild Type	false

molecularNote

Mice carrying Tg(Hba1-Gfp)1Ew were treated with ENU. A C to A transversion in exon 25 results in a T to K amino acid residue change in the proximal bromo-adjacent homology domain.

mutations:
Single point mutation

earliestPublication:
Blewitt ME, et al. (2005) An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse. Proc Natl Acad Sci U S A 102(21):7629-34

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

7 Publication categories

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