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Allele : Lmna<tm3Stw> lamin A; targeted mutation 3, Colin L Stewart

Primary Identifier  MGI:3588578 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Lmna
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An N195K missense mutation was introduced into exon 3 but did not affect the expression levels or the stability of the transcript. A mutant lamin C protein was detected in hearts, however, the expression was less than that of wild-type, suggesting that the protein was less stable than the wild-type protein.
  • mutations:
  • Insertion
  • synonyms:
  • LMNA-N195K,
  • LMNA-N195K
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories