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Allele : Dicer1<tm1Bdh> dicer 1, ribonuclease type III; targeted mutation 1, Brian D Harfe

Primary Identifier  MGI:3589208 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Dicer1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert loxP sites around the exon that encodes most of the second RNaseIII domain as well as an frt-flanked neo within the loxP-encompassed sequence. Cre-mediated removal of the sequence would result in the loss of 90 amino acids, a loss that does not create a downstream frame-shift or an unstable protein.
  • mutations:
  • Insertion
  • synonyms:
  • Dcr<flox>,
  • Dicer<lox>,
  • Dcr<flox>,
  • Dicer1<fl>,
  • Dicer1<fl>,
  • Dicer<flox>,
  • Dcr<fx>,
  • dicer<fl>,
  • Dicer<flox>,
  • dicer<fl>,
  • Dicer<lox>,
  • Dcr<fx>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

240 Publication categories

Trail: Allele