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Allele : Ccdc62<repro29> coiled-coil domain containing 62; reproductive mutant 29, JAX Reproductive Mutagenisis Program

Primary Identifier  MGI:3590192 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Ccdc62
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  ENU mutagenesis created a C>T point mutation in exon 6, changing arginine codon CGA to stop codon TGA (p.Arg284Stop or p.R284*) in the highly conserved second coiled-coil domain. Western blot analysis showed the expression of a truncated peptide from this allele and qRT-PCR showed a significant reduction of mRNA expression from the allele in testes.
  • mutations:
  • Single point mutation
  • synonyms:
  • G1-485-3,
  • G1-485-3
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories