Primary Identifier | MGI:3603004 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Kit |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting construct was designed to introduce a lysine to glutamic acid mutation at amino acid position 641 (K641E) in exon 13. A loxP flanked neomycin resistance gene was included in the targeting vector in intron 13. Position 641 is within the first portion of the slpit kinase domain. |