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Allele : Kit<tm1Bpr> KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Brian P Rubin

Primary Identifier  MGI:3603004 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Kit
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to introduce a lysine to glutamic acid mutation at amino acid position 641 (K641E) in exon 13. A loxP flanked neomycin resistance gene was included in the targeting vector in intron 13. Position 641 is within the first portion of the slpit kinase domain.
  • mutations:
  • Insertion
  • synonyms:
  • Kit<K641E:Neo>,
  • Kit<K641E:Neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories