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Allele : Rigi<tm1Aki> RNA sensor RIG-I; targeted mutation 1, Shizuo Akira

Primary Identifier  MGI:3589395 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rigi
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace a 3.6 kb fragment encoding the ORF, exons 8-10, with a neomycin resistance gene and HSV-TK driven by the PGK promoter. Northern blot and Western blot of MEFs confirmed absence of transcript and protein, respectively.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • RIGI<->,
  • RIG-I<->,
  • Ddx58<->,
  • RIGI<->,
  • RIG-I<->,
  • Ddx58<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

39 Publication categories