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Allele : Thrb<tm5Few> thyroid hormone receptor beta; targeted mutation 5, Fredric E Wondisford
Primary Identifier  MGI:3603187 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Thrb
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Glutamic acid codon 457 (GAA) in exon 10 was changed to alanine (GCA) (p.E457A). A self-excising ACN cassette (loxP site + testis-specific ACE promoter driven cre gene + neomycin resistance gene cassette + loxP site) was inserted into intron 9.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • TR-Beta<E457A>,
  • TR-Beta<E457A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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