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Allele : Fgfr2<tm2Cxd> fibroblast growth factor receptor 2; targeted mutation 2, Chu-Xia Deng

Primary Identifier  MGI:3604072 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Fgfr2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a GG substitution resulted in a Ser250Trp mutation in exon 7. A floxed neo was inserted upstream of exon 7. This allele was a hypomorph, expressed only in significantly reduced levels. Removal of the floxed neo restores expression levels.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Fgfr2<neo250>,
  • Fgfr2<neo250>,
  • Fgfr2<Neo-S252W>,
  • Fgfr2<Neo-S252W>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories