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Allele : Trpc5<tm1.1Mfre> transient receptor potential cation channel, subfamily C, member 5; targeted mutation 1.1, Marc Freichel

Primary Identifier  MGI:6383454 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph, Reporter Gene  Trpc5
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 4. A floxed cassette with a splice acceptor, IRES, and GFP reporter gene were inserted downstream of exon 4. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette previously located within the reporter cassette. Immunohistochemistry confirms the reduction in transcript expression in ARC neurons.
  • mutations:
  • Insertion
  • synonyms:
  • Trpc5<L3F1>,
  • Trpc5<L3F1>,
  • Trpc5-E4fx,
  • Trpc5-E4fx
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories