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Allele : Htt<tm3Szi> huntingtin; targeted mutation 3, Scott Zeitlin

Primary Identifier  MGI:3603606 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Reporter Gene  Htt
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to delete the (CAG)2CAA(CAG)4 triplet repeat encoding 7 glutamines within exon 1. A FLAG epitope tag was included at the N-terminus of the coding sequence in exon 1 to follow expression. A floxed PGK-neo was inserted ~1.3 kb upstream of the transcriptional start site in the opposite transcription orientation.
  • mutations:
  • Insertion
  • synonyms:
  • Hdh<deltaQ>,
  • Hdh<deltaQ>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories