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Allele : Tg(Eno2-APPSwe)1223-3Ykk transgene insertion 1223-3, Yong K Kim

Primary Identifier	MGI:3603946	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Eno2-APPSwe)1223-3Ykk
Strain of Origin	(C57BL/6 x DBA/2)F1	Is Recombinase	false
Is Wild Type	false

molecularNote

The neuron specific rat enolase 2 promoter was used to drive expression of the amyloid protein precursor bearing the Swedish mutation (K670N/M671L). In this line, the APP proteins were highly expressed in brain tissue.

mutations:
Insertion

synonyms:
Am1223-3,
Am1223-3

earliestPublication:
Hwang DY, et al. (2004) Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw. Exp Neurol 186(1):20-32

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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