|  Help  |  About  |  Contact Us

Allele : Rr148<tm1.1Fwa> regulatory region 148; targeted mutation 1.1, Frederick W Alt

Primary Identifier  MGI:3604300 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Rr148
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated excision was used to remove the loxP site flanked neomycin resistance gene cassette that replaced the core Emu enhancer, located between the Igh J and Cmu gene segments. These mice had reduced B cell numbers in association with impaired D to JH and VH to DJH rearrangement.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Igh<tm1.1Fwa>,
  • cEmu<delta>,
  • cEmu<delta>,
  • Igh<tm1.1Fwa>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories