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Allele : Cradd<tm1Mak> CASP2 and RIPK1 domain containing adaptor with death domain; targeted mutation 1, Tak W Mak

Primary Identifier	MGI:3604302	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cradd
Transmission	Germline	Strain of Origin	129
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 1 was replaced with a neomycin resistance gene. Northern blot confirmed the lack of RNA expression in mutant liver samples.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
RAIDD<->,
RAIDD<->

earliestPublication:
Berube C, et al. (2005) Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD. Proc Natl Acad Sci U S A 102(40):14314-20

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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