|  Help  |  About  |  Contact Us

Allele : Htr1f<tm1Dgen> 5-hydroxytryptamine (serotonin) receptor 1F; targeted mutation 1, Deltagen

Primary Identifier  MGI:3604523 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Htr1f
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Deltagen
molecularNote  A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. Low levels of RNA transcripts are detectable in brain, cortex, subcortical region, brainstem, olfactory bulb, large intestine, cecum and testis. No RNA transcripts are detectable in cerebellum, spinal cord, eye, Harderian glands, heart, lung, liver, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, pituitary gland and testis. Most striking expression is observed in brain.
  • mutations:
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele