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Allele : Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd transgene insertion 1, Hugh Robson MacDonald

Primary Identifier  MGI:3607139 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd
Strain of Origin  C57BL/6 x DBA/2 Is Recombinase  false
Is Wild Type  false
molecularNote  The gene segment from human TCR alpha receptor V24 (TRAV24) to TCR alpha receptor JQ (TRAJ18) was fused with the mouse Tcra-C and placed under the control of the human CD2 enhancer promoter. This construct was injected into C57BL/6 x DBA/2 fertilized eggs. Five founders were identified. Founders 1-4 expressed the transgene at a high frequency whereas founder 5 expressed the transgene at a low frequency.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories