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Allele : Apoc3<tm1Lap> apolipoprotein C-III; targeted mutation 1, Len A Pennacchio

Primary Identifier  MGI:3609193 Allele Type  Targeted
Attribute String  Null/knockout Gene  Apoc3
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  ES cells with a hygromycin resistance gene replacing the entire Apoa5 locus were targeted a second time with a vector designed to replace exon 4 of Apoc3 with a neomycin resistance gene. Northern blot revealed that the mutant mice lacked both Apoa5 and Apoc3 transcripts.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories