Primary Identifier | MGI:3609193 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Apoc3 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | ES cells with a hygromycin resistance gene replacing the entire Apoa5 locus were targeted a second time with a vector designed to replace exon 4 of Apoc3 with a neomycin resistance gene. Northern blot revealed that the mutant mice lacked both Apoa5 and Apoc3 transcripts. |