Primary Identifier | MGI:3609219 | Allele Type | QTL |
Gene | Ltxs3 | Inheritance Mode | Dominant |
Strain of Origin | DBA/2NCr | Is Recombinase | false |
Is Wild Type | false |
description | DBA/2AnCr alleles at Ltxs3 confer partial resistance to anthrax lethal toxin. DBA/2AnCr alleles at Kif1c, Ltxs2, and Ltxs3 reconstitute full resistance to anthrax lethal toxin. |
molecularNote | This allele confers resistance to lethal factor (LF) from Bacillus anthracis compared to BALB/cAN. |