Primary Identifier | MGI:3608962 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rhbg |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to insert a copy of exons 2-5 with a 1.7 kb gap in the intronic region adjacent to exon 2, thereby creating an allele with duplicate exons. The vector also contained a puromycin resistance gene, 3' hprt and the K14Agouti transgene. No protein was detected in mutant mice either in the kidney or liver. |