Primary Identifier | MGI:3608690 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ext2 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was replaced by a PGK-neo cassette via homologous recombination. RT-PCR and western blot analysis detected a truncated RNA and protein product in trophoblast stem cells, however heparan sulfate synthesis does not occur. |