|  Help  |  About  |  Contact Us

Allele : Keap1<tm2Mym> kelch-like ECH-associated protein 1; targeted mutation 2, Masayuki Yamamoto

Primary Identifier  MGI:3611748 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Keap1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was created in which exons 4-6 were floxed with loxP sites. This region encodes the double glycine repeat domain. Excision of these exons is predicted to result in generation of a truncated form incapable of repressing Nfe2l2 activity. This allele has reduced expression of the protein and is hypomorphic.
  • mutations:
  • Insertion
  • synonyms:
  • K1-Kd,
  • Keap1<f>,
  • keap1<flox>,
  • K1-Kd,
  • Keap1-kd,
  • Keap1<f>,
  • Keap1-kd,
  • keap1<flox>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

79 Publication categories