| Primary Identifier | MGI:3612049 | Allele Type | Targeted |
| Gene | Ep300 | Transmission | Germline |
| Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Portions of the CH1 domain (amino acids 329-379) encoded by exon 4 were deleted and a neomycin resistance cassette flanked by FRT sites was introduced to the downstream intron. Transient infection of the ES cells with a Flp-expressing vector excised the neomycin cassette. RT-PCR confirmed the deletion in mutant MEFs. |
