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Allele : Btk<tm1Witt> Bruton agammaglobulinemia tyrosine kinase; targeted mutation 1, Owen N Witte
Primary Identifier  MGI:3612416 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Btk
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a Y375F mutation into exon 13. Mutant mice showed normal B cell development and function.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Btk Y375F,
  • Btk Y375F
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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