Primary Identifier | MGI:3612989 | Allele Type | Transgenic |
Attribute String | Null/knockout, Transposase | Gene | Sclt1 |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The ubiquitously expressed CAGGS chimeric promoter derived from chicken beta-actin and CMV immediate early promoter sequences drives expression of the sleeping beauty 10 (sb10) transposase. The transgene caused a 3 kb deletion in and inserted into intron 12 of the host gene. RNA-seq confirmed the absence of transcription from exons 13 onward. |