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Allele : Sclt1<Tg(CAG-sb10)1Dla> sodium channel and clathrin linker 1; transgene insertion 1, David A Largaespada

Primary Identifier  MGI:3612989 Allele Type  Transgenic
Attribute String  Null/knockout, Transposase Gene  Sclt1
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The ubiquitously expressed CAGGS chimeric promoter derived from chicken beta-actin and CMV immediate early promoter sequences drives expression of the sleeping beauty 10 (sb10) transposase. The transgene caused a 3 kb deletion in and inserted into intron 12 of the host gene. RNA-seq confirmed the absence of transcription from exons 13 onward.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CAGGS-SB10,
  • Tg(CAG-sb10)1Dla,
  • CAGGS-SB10,
  • Tg(CAG-sb10)1Dla,
  • Tg(ACTB-sb10)1Dla,
  • Tg(ACTB-sb10)1Dla
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele