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Allele : Hoxd<tm21(Hoxd11)Ddu> homeobox D cluster; targeted mutation 21, Denis Duboule

Primary Identifier  MGI:3616018 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hoxd
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was created in the same ES cells used to create Hoxdtm18.1(Hoxd11)Ddu and thus has a Hoxd11/lacZ/loxP site located 5' of Hoxd13. A lacZ reporter sequence followed by a PGKneo selection cassette was inserted into exon 2 of Hoxd1. In vitro cre expression removed the entire Hoxd cluster replacing it with a Hoxd11/lacZ fusion gene.
  • mutations:
  • Intergenic deletion,
  • Intragenic deletion
  • synonyms:
  • TgH(d11/lac/Del9)Ge,
  • Del(2Hoxd1-Hoxd13)1Ddu,
  • Del(2Hoxd1-Hoxd13)1Ddu,
  • Del1Ddu,
  • Del1Ddu,
  • TgH(d11/lac/Del9)Ge,
  • del(1-13),
  • del(1-13)
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1 Feature

Genome

0 Expresses

16 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

20 Publication categories