| Primary Identifier | MGI:3614340 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(MMTV-PyVT*Y315F*Y322F)Db-1Mul |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| description | Total of 7 lines were produced, of which six lines Db-1, Db-3, Db-4, Db-5, Db-6 and Db-7 had similar phenotype. These mice were used to study metastatic disease and they had similar phenotype. |
| molecularNote | This transgene expresses mutant plyomavirus middle T antigen with Y to F mutation at position 315 and 322 under the control of the mouse mammary tumor virus LTR. Expression of this transgene was detected at high levels in male and female mammary glands. Other expression sites include salivary gland, seminal vesicles, ovaries, and lung. |
